Profile:

Dr. Jay C. Means
Hometown: Chicago, Il

Occupation:

Professor of Toxicology and Environmental Chemistry, Southern Illinois Unviversity, Carbondale, ll.

Undergraduate:

B.S. in Education, University of Illinois, Urbana, IL 1969

Graduate:

M.A. Curriculum Development, Concordia Teacher’s College, River Forest Il, 1971

M.S. University of Illinois, Urbana, IL 1975

Ph.D. University of Illinois, Urbana, IL 1976

Professional Positions:

Assistant and Associate Professor: University of Maryland (1979-1987)

Professor: Louisiana  State University (1987-1997)

Chairman and Professor: Western Michigan University (1997-2007)

Dean and Professor: Southern Illinois University (2007-present)

Interests:

Environmental Chemistry

Chemodynamics of trace organics, trace metals and organometallics in sediment-water systems

Environmental Toxicology 

Awards:  

2007
Awarded Diplomate of the American Board of Toxicology

Admitted as Fellow of the American College of Toxicology

2002
Named Gwen Frostic Professor of Toxicology and Environmental Chemistry WMU

Named as an NSF Ethics Fellow- WMU

1998
Phi Kappa Phi- Faculty nomination and election-WMU

1996
Named as an LSU Alumni Assoc. Distinguished Professor-LSU

1996
Aesculapian Distinguished Lecturer-LSU School of Veterinary Medicine

1994
Distinguished Scholar Award/LSU School of Veterinary Medicine

1984
Awarded NSF Faculty Fellowship.

1975
American Oil Chemists' Society Honored Student Award.

1974
Admitted to Gamma Sigma Delta Honor Society

1969
Admitted to Sigma Xi Scientific Honor Society

 

Dr. Jay C. Means

Dr. Jay C. Means Dr. Means, Dean of the College of Science and Professor of Toxicology and Chemistry in the Department of Chemistry at SIUC, and also Professor of Toxicology in the Department of Pharmacology at the SIU Medical School, came to SIUC in 2007.  Over the course of his career, Dr. Means has been involved in the development and application of trace analytical methodology to the analysis of environmental media including water, sediments, biological tissues, colloidal materials and air using
state-of-the-art instrumentation, including high resolution gas chromatography (HRGC), high performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC/MS), LC/MS/MS and ICP/MS and has published over 100 papers in the area of analytical chemistry, environmental chemistry and toxicology of hydrophobic organic chemicals in aquatic systems including major river systems, estuaries and coastal marine regions.  He has been the principal investigator of dozens of grants and contracts totaling over $15 million dollars dealing specifically with chemical and toxicological assessments of the fate, bioconcentration and effects of organic substances on aquatic organisms, mammals and man.

Dr. Means has an established research and publication record concerning chemodynamic processes which govern the fate and distribution of hydrophobic organics in aquatic environments with special emphasis on soils/sediments and colloidal organic matter and has worked with herbicides, hydrocarbons, PCBs and pesticides in these studies for over 30 years.  He has extended that knowledge of exposure systems into the areas of genetic toxicology and chemical carcinogenesis of environmental agents.  Since 1983, Dr. Means has been studying DNA damage using a variety of measures including chromosomal aberration, gene mutation using bacterial tester strains and more recently carcinogenesis using DNA adduct detection, immunohistochemical, histopathological and molecular genetic methods.  Since 1993, he has been program manager of a multi-investigator, multi-institutional US DOE and US EPA grants (totaling $ 8.4M) to develop toxicological indices of risk associated with energy-related wastes using modern molecular biological methods. He is currently serving as Dean of the College of Science at SIUC where his efforts are devoted to expanding and strengthening the academic programs and research productivity of the College.  In total, Dr. Means has advised or is currently advising 26 doctoral students and 12 Masters student in the fields of toxicology, environmental toxicology and chemistry.

Publications

Peer-reviewed Jounals:
Boudreau, M.D., Taylor, H.W, Goad, M.E., Baker, D.G., and Means, J.C. 2006. A Morphological and Immunocytochemical Study of Pancreatic Changes Induced by Ingestion of 2-Aminoanthracene in the Fisher 344 Rat. Toxicological Sciences 93:50-61

Shuchman, R., Korosov, A., Hatt, C., Pozdnyako, D., Means, J.C. and Meadows, G.  2006 Verification and Application of a Bio-Optical Algorithm for Lake Michigan using SeaWiFS: A Seven Year Interannual Analysis.  J. Great Lakes Res. 32: 258-279. (Chandler-Misener Award paper in 2007)

Fisher, M.A., R. Eversole, C. DeLong, J. C. Means, D. Mihalko, and C. F. Ide. 2008 Liver cyp1A proteinexpression and pimented macrophage aggregates as indicators of polychlorinated biphenyl exposure incarp (Cyprinus carpio) from the Kalamazoo River Superfund Site, MI., Journal of Fish Biology 72:1650-1675.

Chiang, P-C and Means, JC.  2008 Quantification of Benzo[a]pyrene-guanine Adducts in in vitro and in vivo tissue Samples by LC Tandem Mass Spectrometry.  J. Liquid Chromatogr. 31:3169-3193.

Jemal, A., Barker, S.A., and Means, J.C. 2010. Dose-Response Relationship, Kinetics of Formation and Persistence of S-[2-(N7-guanyl) ethyl]glutathione DNA Adduct in Livers of Channel Catfish (Ictalurus punctatus) Exposed in vivo  to 1, 2-Dichloroethan. Environ. Toxicol. Chem. 29: 1537-1444

Lentz, S., Eversole, R. Law, J.M. and Means, J.C. 2010 Cellular Proliferation, Cell Death and Histology of G. affinis Livers After Exposure to Benzidine and 2-Aminofluorene Int. J. Toxicol.  29: 247-258

Connelly, H, and Means, J.C. 2010 Immunomodulatory Effects of Dietary Exposure to Selected Polycyclic Aromatic Hydrocarbons in the Bluegill (Lepomis macrochirus). Int. J. Toxicol. 29: 532-545.

N’Jai, A.U., and Means, JC.  2010 Gene Expression Changes In Fisher 344 Rat Livers After Dietary Exposure To Benzo[a]Pyrene Analyzed By Real-Time Quantitative PCR. Int. J. Toxicol.   In review

Gato WE and Means JC. 2011 Changes in Pancreatic Gene Expression Patterns Due to 2-Aminoanthracene Exposure. J Pharmacol Toxicol 6 (3):234-248.

Gato WE and J.C. Means 2011 Single Cell Gel Electrophoretic Analysis of 2-Aminoanthracene Exposed F-344 Rats, In Press

Books and Monographs:
Analyzing Effects Associated with Lead Exposure by Gene Expression. W.E. Gato and J.C. Means, 2009. Verlag Dr Muller, Saarbruecken, Germany.