ZOOL 409: HISTOLOGY

Department of Zoology
Southern Illinois University at Carbondale

Slide 03

Developing bone, unspecified source.  This specimen represents the end (epiphysis and metaphysis) of a cartilage model undergoing endochondral ossification.  Details vary among slide boxes, but all show an advancing front where cartilage is being replaced by bone.  This region will eventually become the epiphyseal growth plate.  In some specimens, centers of ossification also appear within the epiphysis.  Osteocytes line up along he growing bony spicules in the metaphysis; in some specimens remodelling by osteoclasts can also be found.

Active remodelling, with good examples of osteoblasts and osteoclasts, be seen more clearly on slide 04 from Boxes 3, 5, 6.

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SIUC / College of Science / Zoology / David King / ZOOL 409